Othermatchupshave come close perhaps, like Cristina and Owen and Callie and Arizona (viaScreenrantandVulture).

And so are fans, with some hoping a spinoff is in the works featuring the on-again-off-again lovers.

Our stuff was its own tunnel."

Jesse Williams and Sarah Drew smile together at a party

She returned in 2021 to help Jackson’s storyline wrap up before Williams bid “Grey’s” adieu.

Japril on “Grey’s Anatomy”